WebArtigo publicado na revista "Transactions of the Royal Society of Tropical Medicine and Hygiene" pela Universidade de Oxford, sob o título "Innovative methodology for point-of-care circulating cathodic antigen with rapid urine concentration for use in the field for detecting low Schistosoma mansoni infection and for control of cure with high ... WebFor the rapid and simple diagnosis of schistosomiasis, a reagent strip assay for detection of circulating cathodic antigen (CCA) in urine was developed. The test was based on a previously developed sandwich enzyme-linked immunosorbent assay (ELISA) using a combination of two anti-CCA monoclonal antibodies.
(PDF) Application of a circulating-cathodic-antigen (CCA) …
WebBackground Schistosoma antigen detection in urine is a valuable diagnostic approach for schistosomiasis control programmes because of the higher sensitivity compared to parasitological methods and preferred sampling of urine over stool. Highly Webanticoagulant. [ an″te-, an″ti-ko-ag´u-lant] 1. serving to prevent the coagulation of blood. 2. any substance that, in vivo or in vitro, suppresses, delays, or nullifies coagulation of the … gbf apple key
Evaluation of microscopy, serology, circulating anodic antigen …
WebMar 9, 2024 · The concentration of these antigens in the circulation reflects the presence of viable worms, while the rapid excretion through urine makes noninvasive detection of an active infection feasible. The urine-based lateral flow (LF) point-of-care CCA (POC-CCA) assay has been widely tested in both field and clinical settings. WebDec 22, 2024 · Schistosome worms regurgitate various antigens into the blood circulation, which are then excreted via the urine, for example the antigens ‘circulating cathodic antigen’ (CCA) and ‘circulating anodic … WebJan 24, 2013 · The CCA rapid diagnostic test (Rapid Medical Diagnostics, Pretoria, RSA) is an immunochromatographic dipstick that detects the presence schistosome antigens (proteoglycans), as released from … gbf anima-animus core